Tau Monoclonal Antibody Generation Based on Humanized Yeast Models: IMPACT ON TAU OLIGOMERIZATION AND DIAGNOSTICS

A link between Tau phosphorylation and aggregation has been shown in different models for Alzheimer disease, including yeast. We used human Tau purified from yeast models to generate new monoclonal antibodies, of which three were further characterized. The first antibody, ADx201, binds the Tau proli...

詳細記述

保存先:
書誌詳細
出版年:J Biol Chem
主要な著者: Rosseels, Joëlle, Van den Brande, Jeff, Violet, Marie, Jacobs, Dirk, Grognet, Pierre, Lopez, Juan, Huvent, Isabelle, Caldara, Marina, Swinnen, Erwin, Papegaey, Anthony, Caillierez, Raphaëlle, Buée-Scherrer, Valerie, Engelborghs, Sebastiaan, Lippens, Guy, Colin, Morvane, Buée, Luc, Galas, Marie-Christine, Vanmechelen, Eugeen, Winderickx, Joris
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2015
主題:
Neurobiology
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4326816/
https://ncbi.nlm.nih.gov/pubmed/25540200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.627919
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!

類似資料