S100A4 promotes pancreatic cancer progression through a dual signaling pathway mediated by Src and focal adhesion kinase

S100A4 expression is associated with poor clinical outcomes of patients with pancreatic cancer. The effects of loss or gain of S100A4 were examined in pancreatic cancer cell lines. S100A4 downregulation remarkably reduces cell migration and invasion, inhibits proliferation, and induces apoptosis in...

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Opis bibliograficzny
Wydane w:Sci Rep
Główni autorzy: Che, Pulin, Yang, Youfeng, Han, Xiaosi, Hu, Meng, Sellers, Jeffery C., Londono-Joshi, Angelina I., Cai, Guo-Qiang, Buchsbaum, Donald J., Christein, John D., Tang, Qinjiu, Chen, Dongquan, Li, Qianjun, Grizzle, William E., Lu, Yin Ying, Ding, Qiang
Format: Artigo
Język:Inglês
Wydane: Nature Publishing Group 2015
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Article
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4326725/
https://ncbi.nlm.nih.gov/pubmed/25677816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep08453
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