S100A4 promotes pancreatic cancer progression through a dual signaling pathway mediated by Src and focal adhesion kinase

S100A4 expression is associated with poor clinical outcomes of patients with pancreatic cancer. The effects of loss or gain of S100A4 were examined in pancreatic cancer cell lines. S100A4 downregulation remarkably reduces cell migration and invasion, inhibits proliferation, and induces apoptosis in...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Che, Pulin, Yang, Youfeng, Han, Xiaosi, Hu, Meng, Sellers, Jeffery C., Londono-Joshi, Angelina I., Cai, Guo-Qiang, Buchsbaum, Donald J., Christein, John D., Tang, Qinjiu, Chen, Dongquan, Li, Qianjun, Grizzle, William E., Lu, Yin Ying, Ding, Qiang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4326725/
https://ncbi.nlm.nih.gov/pubmed/25677816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep08453
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