S100A4 promotes pancreatic cancer progression through a dual signaling pathway mediated by Src and focal adhesion kinase

S100A4 expression is associated with poor clinical outcomes of patients with pancreatic cancer. The effects of loss or gain of S100A4 were examined in pancreatic cancer cell lines. S100A4 downregulation remarkably reduces cell migration and invasion, inhibits proliferation, and induces apoptosis in...

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Publicado en:Sci Rep
Autores principales: Che, Pulin, Yang, Youfeng, Han, Xiaosi, Hu, Meng, Sellers, Jeffery C., Londono-Joshi, Angelina I., Cai, Guo-Qiang, Buchsbaum, Donald J., Christein, John D., Tang, Qinjiu, Chen, Dongquan, Li, Qianjun, Grizzle, William E., Lu, Yin Ying, Ding, Qiang
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4326725/
https://ncbi.nlm.nih.gov/pubmed/25677816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep08453
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