Spermidine induces autophagy by inhibiting the acetyltransferase EP300

Several natural compounds found in health-related food items can inhibit acetyltransferases as they induce autophagy. Here we show that this applies to anacardic acid, curcumin, garcinol and spermidine, all of which reduce the acetylation level of cultured human cells as they induce signs of increas...

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Bibliografiska uppgifter
I publikationen:Cell Death Differ
Huvudupphovsmän: Pietrocola, F, Lachkar, S, Enot, D P, Niso-Santano, M, Bravo-San Pedro, J M, Sica, V, Izzo, V, Maiuri, M C, Madeo, F, Mariño, G, Kroemer, G
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2015
Ämnen:
Original Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4326581/
https://ncbi.nlm.nih.gov/pubmed/25526088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2014.215
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