Inhibitor of growth protein 4 interacts with Beclin 1 and represses autophagy

Beclin 1 (BECN1) is a multifunctional protein that activates the pro-autophagic class III phosphatidylinositol 3-kinase (PIK3C3, best known as VPS34), yet also interacts with multiple negative regulators. Here we report that BECN1 interacts with inhibitor of growth family member 4 (ING4), a tumor su...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Sica, Valentina, Bravo-San Pedro, José Manuel, Chen, Guo, Mariño, Guillermo, Lachkar, Sylvie, Izzo, Valentina, Maiuri, Maria Chiara, Niso-Santano, Mireia, Kroemer, Guido
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper: Autophagy and Cell Death
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5685689/
https://ncbi.nlm.nih.gov/pubmed/29163768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19033
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