تحميل...
Structure-function analysis of USP1: insights into the role of Ser313 phosphorylation site and the effect of cancer-associated mutations on autocleavage
BACKGROUND: In complex with its cofactor UAF1, the USP1 deubiquitinase plays an important role in cellular processes related to cancer, including the response to DNA damage. The USP1/UAF1 complex is emerging as a novel target in cancer therapy, but several aspects of its function and regulation rema...
محفوظ في:
| الحاوية / القاعدة: | Mol Cancer |
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| المؤلفون الرئيسيون: | , , |
| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
BioMed Central
2015
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4326527/ https://ncbi.nlm.nih.gov/pubmed/25744535 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-015-0311-7 |
| الوسوم: |
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