Elafin is downregulated during breast and ovarian tumorigenesis but its residual expression predicts recurrence

INTRODUCTION: Elafin is an endogenous serine protease inhibitor. The majority of breast cancer cell lines lack elafin expression compared to human mammary epithelial cells. In this study, we hypothesized that elafin is downregulated during breast and ovarian tumorigenesis. METHODS: We examined elafi...

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Detalhes bibliográficos
Publicado no:Breast Cancer Res
Main Authors: Caruso, Joseph A, Karakas, Cansu, Zhang, Jing, Yi, Min, Albarracin, Constance, Sahin, Aysegul, Bondy, Melissa, Liu, Jinsong, Hunt, Kelly K, Keyomarsi, Khandan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4326485/
https://ncbi.nlm.nih.gov/pubmed/25551582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-014-0497-4
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