RAD18 Activates the G2/M Checkpoint through DNA Damage Signaling to Maintain Genome Integrity after Ionizing Radiation Exposure

The ubiquitin ligase RAD18 is involved in post replication repair pathways via its recruitment to stalled replication forks, and its role in the ubiquitylation of proliferating cell nuclear antigen (PCNA). Recently, it has been reported that RAD18 is also recruited to DNA double strand break (DSB) s...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Sasatani, Megumi, Xu, Yanbin, Kawai, Hidehiko, Cao, Lili, Tateishi, Satoshi, Shimura, Tsutomu, Li, Jianxiang, Iizuka, Daisuke, Noda, Asao, Hamasaki, Kanya, Kusunoki, Yoichiro, Kamiya, Kenji
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4326275/
https://ncbi.nlm.nih.gov/pubmed/25675240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0117845
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