Doripenem MICs and ompK36 Porin Genotypes of Sequence Type 258, KPC-Producing Klebsiella pneumoniae May Predict Responses to Carbapenem-Colistin Combination Therapy among Patients with Bacteremia

Treatment failures of a carbapenem-colistin regimen among patients with bacteremia due to sequence type 258 (ST258), KPC-2-producing Klebsiella pneumoniae were significantly more likely if both agents were inactive in vitro, as defined by a colistin MIC of >2 μg/ml and the presence of either a ma...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Shields, Ryan K., Nguyen, M. Hong, Potoski, Brian A., Press, Ellen G., Chen, Liang, Kreiswirth, Barry N., Clarke, Lloyd G., Eschenauer, Gregory A., Clancy, Cornelius J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Clinical Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4325815/
https://ncbi.nlm.nih.gov/pubmed/25534733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03894-14
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