Characterization of Porin Expression in Klebsiella pneumoniae Carbapenemase (KPC)-Producing K. pneumoniae Identifies Isolates Most Susceptible to the Combination of Colistin and Carbapenems

We characterized carbapenem resistance mechanisms among 12 Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae (referred to here as KPC K. pneumoniae) clinical isolates and evaluated their effects on the activity of 2- and 3-drug combinations of colistin, doripenem, and ertapenem. All...

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Bibliographic Details
Main Authors: Hong, Jae H., Clancy, Cornelius J., Cheng, Shaoji, Shields, Ryan K., Chen, Liang, Doi, Yohei, Zhao, Yanan, Perlin, David S., Kreiswirth, Barry N., Nguyen, M. Hong
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2013
Subjects:
Susceptibility
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3632930/
https://ncbi.nlm.nih.gov/pubmed/23459476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02411-12
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