Molecular Analysis of Codon 548 in the rpoB Gene Involved in Mycobacterium tuberculosis Resistance to Rifampin

Most Mycobacterium tuberculosis rifampin-resistant strains have been associated with mutations in an 81-bp rifampin resistance-determining region (RRDR) in the gene rpoB. However, if this region alone were targeted, rifampin-resistant strains with mutations outside the RRDR would not be detected. In...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Horng, Yu-Tze, Jeng, Wen-Yih, Chen, Yih-Yuan, Liu, Che-Hung, Dou, Horng-Yunn, Lee, Jen-Jyh, Chang, Kai-Chih, Chien, Chih-Ching, Soo, Po-Chi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4325785/
https://ncbi.nlm.nih.gov/pubmed/25534743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04374-14
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