Ataxia Telangiectasia Mutated Kinase Mediates NF-κB Serine 276 Phosphorylation and Interferon Expression via the IRF7-RIG-I Amplification Loop in Paramyxovirus Infection

Respiratory syncytial virus (RSV) is a primary etiological agent of childhood lower respiratory tract disease. Molecular patterns induced by active infection trigger a coordinated retinoic acid-inducible gene I (RIG-I)-Toll-like receptor (TLR) signaling response to induce inflammatory cytokines and...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Fang, Ling, Choudhary, Sanjeev, Tian, Bing, Boldogh, Istvan, Yang, Chunying, Ivanciuc, Teodora, Ma, Yinghong, Garofalo, Roberto P., Brasier, Allan R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Cellular Response to Infection
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4325710/
https://ncbi.nlm.nih.gov/pubmed/25520509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02458-14
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