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The Z Proteins of Pathogenic but Not Nonpathogenic Arenaviruses Inhibit RIG-i-Like Receptor-Dependent Interferon Production

Arenavirus pathogens cause a wide spectrum of diseases in humans ranging from central nervous system disease to lethal hemorrhagic fevers with few treatment options. The reason why some arenaviruses can cause severe human diseases while others cannot is unknown. We find that the Z proteins of all kn...

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Publicat a:J Virol
Autors principals: Xing, Junji, Ly, Hinh, Liang, Yuying
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4325705/
https://ncbi.nlm.nih.gov/pubmed/25552708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03349-14
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