Differential Inhibition of Macrophage Activation by Lymphocytic Choriomeningitis Virus and Pichinde Virus Is Mediated by the Z Protein N-Terminal Domain

Several arenavirus pathogens, such as Lassa and Junin viruses, inhibit macrophage activation, the molecular mechanism of which is unclear. We show that lymphocytic choriomeningitis virus (LCMV) can also inhibit macrophage activation, in contrast to Pichinde and Tacaribe viruses, which are not known...

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Bibliographic Details
Published in:J Virol
Main Authors: Xing, Junji, Chai, Zheng, Ly, Hinh, Liang, Yuying
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2015
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4665234/
https://ncbi.nlm.nih.gov/pubmed/26423945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01674-15
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