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Differential Inhibition of Macrophage Activation by Lymphocytic Choriomeningitis Virus and Pichinde Virus Is Mediated by the Z Protein N-Terminal Domain

Several arenavirus pathogens, such as Lassa and Junin viruses, inhibit macrophage activation, the molecular mechanism of which is unclear. We show that lymphocytic choriomeningitis virus (LCMV) can also inhibit macrophage activation, in contrast to Pichinde and Tacaribe viruses, which are not known...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Xing, Junji, Chai, Zheng, Ly, Hinh, Liang, Yuying
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4665234/
https://ncbi.nlm.nih.gov/pubmed/26423945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01674-15
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