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Z Proteins of New World Arenaviruses Bind RIG-I and Interfere with Type I Interferon Induction
The retinoic acid-inducible gene I product (RIG-I) is a cellular sensor of RNA virus infection that regulates the cellular beta interferon (IFN-β) response. The nucleoproteins (NP) of arenaviruses are reported to antagonize the IFN response by inhibiting interferon regulatory factor 3 (IRF-3). Here,...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Microbiology (ASM)
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2812374/ https://ncbi.nlm.nih.gov/pubmed/20007272 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01362-09 |
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