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Influenza A Virus Panhandle Structure Is Directly Involved in RIG-I Activation and Interferon Induction

Retinoic acid-inducible gene I (RIG-I) is an important innate immune sensor that recognizes viral RNA in the cytoplasm. Its nonself recognition largely depends on the unique RNA structures imposed by viral RNA. The panhandle structure residing in the influenza A virus (IAV) genome, whose primary fun...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Liu, GuanQun, Park, Hong-Su, Pyo, Hyun-Mi, Liu, Qiang, Zhou, Yan
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4442436/
https://ncbi.nlm.nih.gov/pubmed/25810557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00232-15
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