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Influenza A Virus Panhandle Structure Is Directly Involved in RIG-I Activation and Interferon Induction
Retinoic acid-inducible gene I (RIG-I) is an important innate immune sensor that recognizes viral RNA in the cytoplasm. Its nonself recognition largely depends on the unique RNA structures imposed by viral RNA. The panhandle structure residing in the influenza A virus (IAV) genome, whose primary fun...
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| Publicado no: | J Virol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4442436/ https://ncbi.nlm.nih.gov/pubmed/25810557 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00232-15 |
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