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Influenza A Virus Panhandle Structure Is Directly Involved in RIG-I Activation and Interferon Induction

Retinoic acid-inducible gene I (RIG-I) is an important innate immune sensor that recognizes viral RNA in the cytoplasm. Its nonself recognition largely depends on the unique RNA structures imposed by viral RNA. The panhandle structure residing in the influenza A virus (IAV) genome, whose primary fun...

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Bibliografske podrobnosti
izdano v:J Virol
Main Authors: Liu, GuanQun, Park, Hong-Su, Pyo, Hyun-Mi, Liu, Qiang, Zhou, Yan
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4442436/
https://ncbi.nlm.nih.gov/pubmed/25810557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00232-15
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