Hijacking of RIG-I Signaling Proteins into Virus-Induced Cytoplasmic Structures Correlates with the Inhibition of Type I Interferon Responses

Recognition of viral pathogens by the retinoic acid-inducible gene I (RIG-I)-like receptor (RLR) family results in the activation of type I interferon (IFN) responses. To avoid this response, most viruses have evolved strategies that target different essential steps in the activation of host innate...

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Autores principales: Santiago, Felix W., Covaleda, Lina M., Sanchez-Aparicio, Maria T., Silvas, Jesus A., Diaz-Vizarreta, Ana C., Patel, Jenish R., Popov, Vsevolod, Yu, Xue-jie, García-Sastre, Adolfo, Aguilar, Patricia V.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2014
Materias:
Virus-Cell Interactions
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993744/
https://ncbi.nlm.nih.gov/pubmed/24478431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03021-13
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