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Variants of a mouse myeloma cell line that synthesize immunoglobulin heavy chains having an altered serotype.

Cells of the MPC-11 mouse myeloma cell line, which produces an IgG2b immunoglobulin, were subjected to mutagenesis with Melphalan or with ICR-191, after which they were cloned in soft agar. Approximately 0.5 percent of the clones produced altered heavy chains that: (i) were the same size as or large...

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Bibliografske podrobnosti
Main Authors: Preud'Homme, J L, Birshtein, B K, Scharff, M D
Format: Artigo
Jezik:Inglês
Izdano: 1975
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC432548/
https://ncbi.nlm.nih.gov/pubmed/805428
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