Загрузка...
14-3-3ζ turns TGF-β’s function from tumor suppressor to metastasis promoter in breast cancer by contextual changes of Smad partners from p53 to Gli2
Transforming growth factor-β (TGF-β) functions as a tumor suppressor in pre-malignant cells but as a metastasis promoter in cancer cells. The dichotomous functions of TGF-β are proposed to be dictated by different partners of its downstream effectors Smads. However, the mechanism for the contextual...
Сохранить в:
| Опубликовано в: : | Cancer Cell |
|---|---|
| Главные авторы: | , , , , , , , , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2015
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4325275/ https://ncbi.nlm.nih.gov/pubmed/25670079 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2014.11.025 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|