14-3-3ζ Orchestrates Mammary Tumor Onset and Progression via miR221-Mediated Cell Proliferation

14-3-3ζ is overexpressed in over 40% of breast cancers but its pathophysiological relevance to tumorigenesis has not been established. Here we show that 14-3-3ζ overexpression is sufficient to induce tumorigenesis in a transgenic mouse model of breast cancer. MMTV-LTR promoter driven HA-14-3-3ζ tran...

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Detalhes bibliográficos
Main Authors: Rehman, Sumaiyah K., Li, Shau-Hsuan, Wyszomierski, Shannon L., Wang, Qingfei, Li, Ping, Sahin, Ozgur, Xiao, Yi, Zhang, Siyuan, Xiong, Yan, Yang, Jun, Wang, Hai, Guo, Hua, Zhang, Jitao D., Medina, Daniel, Muller, William J., Yu, Dihua
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947305/
https://ncbi.nlm.nih.gov/pubmed/24197133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-2016
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