14-3-3ζ Orchestrates Mammary Tumor Onset and Progression via miR221-Mediated Cell Proliferation

14-3-3ζ is overexpressed in over 40% of breast cancers but its pathophysiological relevance to tumorigenesis has not been established. Here we show that 14-3-3ζ overexpression is sufficient to induce tumorigenesis in a transgenic mouse model of breast cancer. MMTV-LTR promoter driven HA-14-3-3ζ tran...

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Bibliografiske detaljer
Main Authors: Rehman, Sumaiyah K., Li, Shau-Hsuan, Wyszomierski, Shannon L., Wang, Qingfei, Li, Ping, Sahin, Ozgur, Xiao, Yi, Zhang, Siyuan, Xiong, Yan, Yang, Jun, Wang, Hai, Guo, Hua, Zhang, Jitao D., Medina, Daniel, Muller, William J., Yu, Dihua
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947305/
https://ncbi.nlm.nih.gov/pubmed/24197133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-2016
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