Stable X Chromosome Reactivation in Female Human Induced Pluripotent Stem Cells

In placental mammals, balanced expression of X-linked genes is accomplished by X chromosome inactivation (XCI) in female cells. In humans, random XCI is initiated early during embryonic development. To investigate whether reprogramming of female human fibroblasts into induced pluripotent stem cells...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Barakat, Tahsin Stefan, Ghazvini, Mehrnaz, de Hoon, Bas, Li, Tracy, Eussen, Bert, Douben, Hannie, van der Linden, Reinier, van der Stap, Nathalie, Boter, Marjan, Laven, Joop S., Galjaard, Robert-Jan, Grootegoed, J. Anton, de Klein, Annelies, Gribnau, Joost
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
Assuntos:
Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4325229/
https://ncbi.nlm.nih.gov/pubmed/25640760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2014.12.012
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