Epigenetic Characterization of the FMR1 Promoter in Induced Pluripotent Stem Cells from Human Fibroblasts Carrying an Unmethylated Full Mutation

Silencing of the FMR1 gene leads to fragile X syndrome, the most common cause of inherited intellectual disability. To study the epigenetic modifications of the FMR1 gene during silencing in time, we used fibroblasts and induced pluripotent stem cells (iPSCs) of an unmethylated full mutation (uFM) i...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: de Esch, Celine E.F., Ghazvini, Mehrnaz, Loos, Friedemann, Schelling-Kazaryan, Nune, Widagdo, W., Munshi, Shashini T., van der Wal, Erik, Douben, Hannie, Gunhanlar, Nilhan, Kushner, Steven A., Pijnappel, W.W.M. Pim, de Vrij, Femke M.S., Geijsen, Niels, Gribnau, Joost, Willemsen, Rob
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2014
Assuntos:
Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223701/
https://ncbi.nlm.nih.gov/pubmed/25358783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2014.07.013
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados