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The pluripotency factor-bound intron 1 of Xist is dispensable for X chromosome inactivation and reactivation in vitro and in vivo
X chromosome inactivation (XCI) is a dynamically-regulated developmental process with inactivation and reactivation accompanying the loss and gain of pluripotency, respectively. A functional relationship between pluripotency and lack of XCI has been suggested, whereby pluripotency transcription fact...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3615097/ https://ncbi.nlm.nih.gov/pubmed/23523354 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.02.018 |
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