The pluripotency factor-bound intron 1 of Xist is dispensable for X chromosome inactivation and reactivation in vitro and in vivo

X chromosome inactivation (XCI) is a dynamically-regulated developmental process with inactivation and reactivation accompanying the loss and gain of pluripotency, respectively. A functional relationship between pluripotency and lack of XCI has been suggested, whereby pluripotency transcription fact...

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Bibliografiske detaljer
Main Authors: Minkovsky, Alissa, Barakat, Tahsin Stefan, Sellami, Nadia, Chin, Mark Henry, Gunhanlar, Nilhan, Gribnau, Joost, Plath, Kathrin
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3615097/
https://ncbi.nlm.nih.gov/pubmed/23523354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.02.018
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