Large-Scale Hematopoietic Differentiation of Human Induced Pluripotent Stem Cells Provides Granulocytes or Macrophages for Cell Replacement Therapies

Interleukin-3 (IL-3) is capable of supporting the proliferation of a broad range of hematopoietic cell types, whereas granulocyte colony-stimulating factor (G-CSF) and macrophage CSF (M-CSF) represent critical cytokines in myeloid differentiation. When this was investigated in a pluripotent-stem-cel...

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Publicado en:Stem Cell Reports
Main Authors: Lachmann, Nico, Ackermann, Mania, Frenzel, Eileen, Liebhaber, Steffi, Brennig, Sebastian, Happle, Christine, Hoffmann, Dirk, Klimenkova, Olga, Lüttge, Doreen, Buchegger, Theresa, Kühnel, Mark Philipp, Schambach, Axel, Janciauskiene, Sabina, Figueiredo, Constanca, Hansen, Gesine, Skokowa, Julia, Moritz, Thomas
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4325194/
https://ncbi.nlm.nih.gov/pubmed/25680479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2015.01.005
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