Lataa...

Distinct conformational and functional effects of two adjacent pathogenic mutations in cardiac troponin I at the interface with troponin T

The α-helix in troponin I (TnI) at the interface with troponin T (TnT) is a highly conserved structure. A point mutation in this region, A116G, was found in human cardiac TnI in a case of cardiomyopathy. An adjacent dominantly negative mutation found in turkey cardiac TnI (R111C, equivalent to K117C...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:FEBS Open Bio
Päätekijät: Akhter, Shirin, Jin, J.-P.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Elsevier 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4325132/
https://ncbi.nlm.nih.gov/pubmed/25685665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fob.2015.01.001
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!