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Targeted Protein Destabilization Reveals an Estrogen-mediated ER Stress Response
Accumulation of unfolded proteins within the endoplasmic reticulum (ER) of eukaryotic cells leads to an unfolded protein response (UPR) that either restores homeostasis or commits the cells to apoptosis. Tools traditionally used to study the UPR are pro-apoptotic and thus confound analysis of long-t...
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| Vydáno v: | Nat Chem Biol |
|---|---|
| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4324732/ https://ncbi.nlm.nih.gov/pubmed/25242550 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1638 |
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