Código QR (código de barras bidimensional)

Antitumor bisdioxopiperazines inhibit yeast DNA topoisomerase II by trapping the enzyme in the form of a closed protein clamp.

The mechanism of inhibition of eukaryotic DNA topoisomerase II [DNA topoisomerase (ATP-hydrolyzing), EC 5.99.1.3] by a member of the bisdioxopiperazine family of anticancer drugs, ICRF-193, was investigated by using purified yeast DNA topoisomerase II. In the absence of ATP, ICRF-193 has little effe...

Fuld beskrivelse

Na minha lista:
Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Roca, J, Ishida, R, Berger, J M, Andoh, T, Wang, J C
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1994
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43247/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8127881/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.5.1781
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker