DNA transport by a type II topoisomerase: direct evidence for a two-gate mechanism.

Recent biochemical and crystallographic results suggest that a type II DNA topoisomerase acts as an ATP-modulated clamp with two sets of jaws at opposite ends: a DNA-bound enzyme can admit a second DNA through one set of jaws; upon binding ATP, this DNA is passed through an enzyme-mediated opening i...

Full description

Saved in:
Bibliographic Details
Main Authors: Roca, J, Berger, J M, Harrison, S C, Wang, J C
Format: Artigo
Language:Inglês
Published: 1996
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC39486/
https://ncbi.nlm.nih.gov/pubmed/8633016
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items