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De Novo Design of Self-Assembling Foldamers That Inhibit Heparin–Protein Interactions
[Image: see text] A series of self-associating foldamers have been designed as heparin reversal agents, as antidotes to prevent bleeding due to this potent antithrombotic agent. The foldamers have a repeating sequence of Lys-Sal, in which Sal is 5-amino-2-methoxy-benzoic acid. These foldamers are de...
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| 出版年: | ACS Chem Biol |
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| 主要な著者: | , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American
Chemical
Society
2014
|
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4324449/ https://ncbi.nlm.nih.gov/pubmed/24491145 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb500026x |
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