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De novo design and in vivo activity of conformationally restrained antimicrobial arylamide foldamers

The emergence of drug-resistant bacteria has compromised the use of many conventional antibiotics, leading to heightened interest in a variety of antimicrobial peptides. Although these peptides have attractive potential as antibiotics, their size, stability, tissue distribution, and toxicity have ha...

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Bibliografski detalji
Glavni autori: Choi, Sungwook, Isaacs, Andre, Clements, Dylan, Liu, Dahui, Kim, Hyemin, Scott, Richard W., Winkler, Jeffrey D., DeGrado, William F.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2667368/
https://ncbi.nlm.nih.gov/pubmed/19359494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0811818106
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