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De novo design and in vivo activity of conformationally restrained antimicrobial arylamide foldamers
The emergence of drug-resistant bacteria has compromised the use of many conventional antibiotics, leading to heightened interest in a variety of antimicrobial peptides. Although these peptides have attractive potential as antibiotics, their size, stability, tissue distribution, and toxicity have ha...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2667368/ https://ncbi.nlm.nih.gov/pubmed/19359494 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0811818106 |
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