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Putative E3 Ubiquitin Ligase of Human Rotavirus Inhibits NF-κB Activation by Using Molecular Mimicry To Target β-TrCP

NF-κB plays a critical role in the induction and maintenance of innate and adaptive immune transcriptional programs. An associated inhibitor of κB protein (IκB) regulates NF-κB activation and contains a degron motif (DSGΦxS) that undergoes phosphorylation following pathogen recognition or other proi...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Morelli, Marco, Dennis, Allison F., Patton, John T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4324316/
https://ncbi.nlm.nih.gov/pubmed/25626907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02490-14
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