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Deficiency of antigen-specific B cells results in decreased Trypanosoma cruzi systemic but not mucosal immunity due to CD8 T cell exhaustion
Vaccines against mucosally invasive, intracellular pathogens must induce a myriad of immune responses in order to provide optimal mucosal and systemic protection, including CD4(+) T cells, CD8(+) T cells and antibody-producing B cells. In general, CD4(+) T cells are known to provide important helper...
Gardado en:
| Publicado en: | J Immunol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4324165/ https://ncbi.nlm.nih.gov/pubmed/25595788 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1303163 |
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