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Deficiency of antigen-specific B cells results in decreased Trypanosoma cruzi systemic but not mucosal immunity due to CD8 T cell exhaustion
Vaccines against mucosally invasive, intracellular pathogens must induce a myriad of immune responses in order to provide optimal mucosal and systemic protection, including CD4(+) T cells, CD8(+) T cells and antibody-producing B cells. In general, CD4(+) T cells are known to provide important helper...
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| Publicat a: | J Immunol |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4324165/ https://ncbi.nlm.nih.gov/pubmed/25595788 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1303163 |
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