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Early hyperactivity in lateral entorhinal cortex is associated with elevated levels of AβPP metabolites in the Tg2576 mouse model of Alzheimer’s disease

Alzheimer’s disease (AD) is a neurodegenerative disorder that is the most common cause of dementia in the elderly today. One of the earliest symptoms of AD is olfactory dysfunction. The present study investigated the effects of amyloid β precursor protein (AβPP) metabolites, including amyloid-β (Aβ)...

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Detalhes bibliográficos
Publicado no:Exp Neurol
Main Authors: Xu, Wenjin, Fitzgerald, Shane, Nixon, Ralph A., Levy, Efrat, Wilson, Donald A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4324092/
https://ncbi.nlm.nih.gov/pubmed/25500142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2014.12.008
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