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Early hyperactivity in lateral entorhinal cortex is associated with elevated levels of AβPP metabolites in the Tg2576 mouse model of Alzheimer’s disease

Alzheimer’s disease (AD) is a neurodegenerative disorder that is the most common cause of dementia in the elderly today. One of the earliest symptoms of AD is olfactory dysfunction. The present study investigated the effects of amyloid β precursor protein (AβPP) metabolites, including amyloid-β (Aβ)...

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Pubblicato in:Exp Neurol
Autori principali: Xu, Wenjin, Fitzgerald, Shane, Nixon, Ralph A., Levy, Efrat, Wilson, Donald A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4324092/
https://ncbi.nlm.nih.gov/pubmed/25500142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2014.12.008
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