Entorhinal cortical defects in Tg2576 mice are present as early as 2–4 months of age

The entorhinal cortex (EC) is one of the first brain areas to display neuropathology in Alzheimer’s disease (AD). A mouse model which simulates amyloid-β (Aβ) neuropathology, the Tg2576 mouse, was used to address these early changes. Here we show EC abnormalities occur in 2–4 month-old Tg2576 mice,...

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Detaylı Bibliyografya
Yayımlandı:Neurobiol Aging
Asıl Yazarlar: Duffy, Áine M., Morales-Corraliza, Jose, Bermudez-Hernandez, Keria M., Schaner, Michael J., Magagna-Poveda, Alejandra, Mathews, Paul M., Scharfman, Helen E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4268389/
https://ncbi.nlm.nih.gov/pubmed/25109765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2014.07.001
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