Entorhinal cortical defects in Tg2576 mice are present as early as 2–4 months of age

The entorhinal cortex (EC) is one of the first brain areas to display neuropathology in Alzheimer’s disease (AD). A mouse model which simulates amyloid-β (Aβ) neuropathology, the Tg2576 mouse, was used to address these early changes. Here we show EC abnormalities occur in 2–4 month-old Tg2576 mice,...

Full description

Saved in:
Bibliographic Details
Published in:Neurobiol Aging
Main Authors: Duffy, Áine M., Morales-Corraliza, Jose, Bermudez-Hernandez, Keria M., Schaner, Michael J., Magagna-Poveda, Alejandra, Mathews, Paul M., Scharfman, Helen E.
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4268389/
https://ncbi.nlm.nih.gov/pubmed/25109765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2014.07.001
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items