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Elevation of c-MYC Disrupts HLA Class II-mediated Immune Recognition of Human B-cell Tumors()

Elevated levels of the transcription factor c-myc are strongly associated with various cancers, and in particular B-cell lymphomas. While many of c-MYC’s functions have been elucidated, its effect on the presentation of antigen (Ag) through the HLA class II pathway has not previously been reported....

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Publicat a:J Immunol
Autors principals: God, Jason M., Cameron, Christine, Figueroa, Janette, Amria, Shereen, Hossain, Azim, Kempkes, Bettina, Bornkamm, Georg W., Stuart, Robert K., Blum, Janice S., Haque, Azizul
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4323931/
https://ncbi.nlm.nih.gov/pubmed/25595783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402382
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