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Enhancement of HLA class II-restricted CD4+ T cell recognition of human melanoma cells following treatment with bryostatin-1

The majority of melanoma cells express detectable levels of HLA class II proteins, and an increased threshold of cell surface class II is crucial for the stimulation of CD4+ T cells. Bryostatin-1, a protein kinase C (PKC) activator, has been considered as a potent chemotherapeutic agent in a variety...

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Bibliografiske detaljer
Main Authors: Zhao, Dan, Amria, Shereen, Hossain, Azim, Sundaram, Kumaran, Komlosi, Peter, Nagarkatti, Mitzi, Haque, Azizul
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196280/
https://ncbi.nlm.nih.gov/pubmed/21903207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2011.08.007
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