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Disruption of HLA class II antigen presentation in Burkitt lymphoma: implication of a 47 000 MW acid labile protein in CD4(+) T-cell recognition

While Burkitt lymphoma (BL) has a well-known defect in HLA class I-mediated antigen presentation, the exact role of BL-associated HLA class II in generating a poor CD4(+) T-cell response remains unresolved. Here, we found that BL cells are deficient in their ability to optimally stimulate CD4(+) T c...

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Detalhes bibliográficos
Main Authors: God, Jason M, Zhao, Dan, Cameron, Christine A, Amria, Shereen, Bethard, Jennifer R, Haque, Azizul
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4080965/
https://ncbi.nlm.nih.gov/pubmed/24628049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12281
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