Tasquinimod modulates suppressive myeloid cells and enhances cancer immunotherapies in murine models

A major barrier for cancer immunotherapy is the presence of suppressive cell populations in cancer patients, such as myeloid-derived suppressor cells (MDSC) and tumor-associated macrophages (TAM), which contribute to the immunosuppressive microenvironment that promotes tumor growth and metastasis. T...

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Detalhes bibliográficos
Publicado no:Cancer Immunol Res
Main Authors: Shen, Li, Sundstedt, Anette, Ciesielski, Michael, Miles, Kiersten Marie, Celander, Mona, Adelaiye, Remi, Orillion, Ashley, Ciamporcero, Eric, Ramakrishnan, Swathi, Ellis, Leigh, Fenstermaker, Robert, Abrams, Scott I., Eriksson, Helena, Leanderson, Tomas, Olsson, Anders, Pili, Roberto
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4323929/
https://ncbi.nlm.nih.gov/pubmed/25370534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-14-0036
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