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Asymmetric syntheses of three-membered heterocycles using chiral amide-based ammonium ylides

The use of carbonyl-stabilised ammonium ylides to access chiral glycidic amides and the corresponding aziridines has so far been limited to racemic trans-selective protocols. We herein report the development of an asymmetric approach to access such compounds with high levels of stereoselectivity usi...

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Publicat a:Org Biomol Chem
Autors principals: Pichler, Mathias, Novacek, Johanna, Robiette, Raphaël, Poscher, Vanessa, Himmelsbach, Markus, Monkowius, Uwe, Müller, Norbert, Waser, Mario
Format: Artigo
Idioma:Inglês
Publicat: Royal Society of Chemistry 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4323751/
https://ncbi.nlm.nih.gov/pubmed/25521410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4ob02318h
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