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Assessing Recovery from Neurodegeneration in Spinocerebellar Ataxia 1: Comparison of in vivo Magnetic Resonance Spectroscopy with Motor Testing, Gene Expression and Histology
Suppression of transgene expression in a conditional transgenic mouse model of spinocerebellar ataxia 1 (SCA1) reverses the Purkinje cell pathology and motor dysfunction that are hallmarks of SCA1. We previously showed that cerebellar neurochemical levels measured by magnetic resonance spectroscopy...
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| Publicado no: | Neurobiol Dis |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4323665/ https://ncbi.nlm.nih.gov/pubmed/25446943 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2014.11.011 |
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