Noninvasive Detection of Presymptomatic and Progressive Neurodegeneration in a Mouse Model of Spinocerebellar Ataxia Type 1

Recent studies with a conditional mouse model of spinocerebellar ataxia type 1 (SCA1) suggest that neuronal dysfunction is reversible and neurodegeneration preventable with early interventions. Success of such interventions will depend on early detection of neuronal and glial abnormalities before ce...

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Main Authors: Öz, Gülin, Nelson, Christopher D., Koski, Dee M., Henry, Pierre-Gilles, Marjańska, Małgorzata, Deelchand, Dinesh K., Shanley, Ryan, Eberly, Lynn E., Orr, Harry T., Clark, H. Brent
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2010
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2846771/
https://ncbi.nlm.nih.gov/pubmed/20220018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5612-09.2010
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