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Distinct Amino Acid Compositional Requirements for Formation and Maintenance of the [PSI(+)] Prion in Yeast

Multiple yeast prions have been identified that result from the structural conversion of proteins into a self-propagating amyloid form. Amyloid-based prion activity in yeast requires a series of discrete steps. First, the prion protein must form an amyloid nucleus that can recruit and structurally c...

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Библиографические подробности
Опубликовано в: :Mol Cell Biol
Главные авторы: MacLea, Kyle S., Paul, Kacy R., Ben-Musa, Zobaida, Waechter, Aubrey, Shattuck, Jenifer E., Gruca, Margaret, Ross, Eric D.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2015
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4323492/
https://ncbi.nlm.nih.gov/pubmed/25547291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01020-14
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