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Strategies for identifying new prions in yeast

The unexpected discovery of two prions, [URE3] and [PSI(+)], in Saccharomyces cerevisiae led to questions about how many other proteins could undergo similar prion-based structural conversions. However, [URE3] and [PSI(+)] were discovered by serendipity in genetic screens. Cataloging the full range...

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Detalhes bibliográficos
Main Authors: MacLea, Kyle S, Ross, Eric D
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4012408/
https://ncbi.nlm.nih.gov/pubmed/22052351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.5.4.17918
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