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Compositional Determinants of Prion Formation in Yeast

Numerous prions (infectious proteins) have been identified in yeast that result from the conversion of soluble proteins into β-sheet-rich amyloid-like protein aggregates. Yeast prion formation is driven primarily by amino acid composition. However, yeast prion domains are generally lacking in the bu...

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Detalhes bibliográficos
Main Authors: Toombs, James A., McCarty, Blake R., Ross, Eric D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798286/
https://ncbi.nlm.nih.gov/pubmed/19884345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01140-09
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