Wnt5A regulates ABCB1 expression in multidrug-resistant cancer cells through activation of the non-canonical PKA/β-catenin pathway

Multidrug resistance in cancer cells arises from altered drug permeability of the cell. We previously reported activation of the Wnt pathway in ABCB1-overexpressed human uterus sarcoma drug-resistant MES-SA/Dx5 cells through active β-catenin and associated transactivation activities, and upregulatio...

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Udgivet i:Oncotarget
Main Authors: Hung, Tsai-Hsien, Hsu, Sheng-Chi, Cheng, Ching-Yi, Choo, Kong-Bung, Tseng, Ching-Ping, Chen, Tse-Ching, Lan, Ying-Wei, Huang, Tsung-Teng, Lai, Hsin-Chih, Chen, Chuan-Mu, Chong, Kowit-Yu
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2014
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4322984/
https://ncbi.nlm.nih.gov/pubmed/25401518
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