Wnt pathway activation and ABCB1 expression account for attenuation of Proteasome inhibitor-mediated apoptosis in multidrug-resistant cancer cells

Multiple drug resistance (MDR) is a major obstacle to attenuating the effectiveness of chemotherapy to many human malignancies. Proteasome inhibition induces apoptosis in a variety of cancer cells and is recognized as a novel anticancer therapy approach. Despite its success, some multiple myeloma pa...

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Bibliografiske detaljer
Udgivet i:Cancer Biol Ther
Main Authors: Chong, Kowit Yu, Hsu, Chih-Jung, Hung, Tsai-Hsien, Hu, Han-Shu, Huang, Tsung-Teng, Wang, Tzu-Hao, Wang, Chihuei, Chen, Chuan-Mu, Choo, Kong Bung, Tseng, Ching-Ping
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2015
Fag:
Research Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4623479/
https://ncbi.nlm.nih.gov/pubmed/25590413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384047.2014.987093
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